Specifications
| Size | 50μL/100μL |
| Target | STX17 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 33kD |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1752R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | STX17 |
| Protein Name | STX17 |
| Other Name | |
| Species | Human |
| Gene ID | 55014 |
| Uniprot | P56962, |
| Species.1 | Mouse |
| Gene ID.1 | 67727 |
| Uniprot.1 | Q9D0I4, |
| Species.2 | Rat |
| Gene ID.2 | 252853 |
| Uniprot.2 | Q9Z158 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Smooth endoplasmic reticulum membrane; Multi-pass membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein . Cytoplasm, cytosol . Mitochondrion membrane; Multi-pass membrane protein . Has a hairpin-like insertion into membranes. Localizes to the completed autophagosome membrane upon cell starvation (PubMed:23217709). . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal |
| Research Areas | >>SNARE interactions in vesicular transport; / >>Autophagy - animal |
| Function | Function:Implicated in vesicle trafficking to lysosomes. Could be involved in processes related to cell division.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,subcellular location:Appears to be associated with a membrane compartment, perhaps a subset of the ER such as exit or entrance sites., |
