Product details
Background：
U-Blot® TAX1BP1 Rabbit mAb
Ucallm_WR6049-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TAX1BP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 91kD |
| MW(Observed) | 100kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM2017R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | TAX1BP1 T6BP PRO0105 |
| Protein Name | Tax1-binding protein 1 (TRAF6-binding protein) |
| Other Name | |
| Species | Human |
| Gene ID | 8887 |
| Uniprot | Q86VP1, |
| Species.1 | Mouse |
| Gene ID.1 | 52440 |
| Uniprot.1 | Q3UKC1, |
| Species.2 | Rat |
| Gene ID.2 | 246244 |
| Uniprot.2 | Q66HA4 |
| Cellular Localization | |
| Tissue Expression | Expressed in all tissues tested. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Cellular Processes >> Transport and catabolism >> Mitophagy - animal |
| Research Areas | |
| Function | Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. |
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