U-Blot® TCP 1 η Rabbit mAb
Ucallm_WR6033-50
Price range: $268.00 through $328.00
Product details
Background：
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT) , also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings , each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins , including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq , Oct 2009] ,
Specifications
| Size | 50μL/100μL |
| Target | TCP-1 η |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | 59kD |
| MW(Observed) | 59kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM2029R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | CCT7 |
| Protein Name | T-complex protein 1 subunit eta |
| Other Name | CCT7; / CCTH; / NIP7-1; / T-complex protein 1 subunit eta; / TCP-1-eta; / CCT-eta; / HIV-1 Nef-interacting protein |
| Species | Human |
| Gene ID | 10574 |
| Uniprot | Q99832, |
| Species.1 | Mouse |
| Gene ID.1 | 12468 |
| Uniprot.1 | P80313 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Adipose tissue,Brain,Cajal-Retzius cell,Cerebellum,Colon carcinoma, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the chaperonin (HSP60) family.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG., |
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