U-Blot® Thymidine Kinase Rabbit mAb
Ucallm_WR5903-50
Price range: $268.00 through $328.00
Product details
Background：
catalytic activity:ATP + thymidine = ADP + thymidine 5′-phosphate. ,miscellaneous:Two forms have been identified in animal cells , one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. ,PTM:Phosphorylated on Ser-13 in mitosis. ,similarity:Belongs to the thymidine kinase family. ,
Specifications
| Size | 50μL/100μL |
| Target | Thymidine Kinase |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 26kD |
| MW(Observed) | 26kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1844R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | TK1 |
| Protein Name | Thymidine kinase cytosolic |
| Other Name | TK1; / Thymidine kinase; / cytosolic |
| Species | Human |
| Gene ID | 7083 |
| Uniprot | P04183, |
| Species.1 | Mouse |
| Gene ID.1 | 21877 |
| Uniprot.1 | P04184, |
| Species.2 | Rat |
| Gene ID.2 | 24834 |
| Uniprot.2 | P27158 |
| Cellular Localization | Cytoplasm. |
| Tissue Expression | Epithelium,Lymph,Skin,Uterus, |
| Signaling_pathway | |
| Research Areas | >>Pyrimidine metabolism; / >>Drug metabolism - other enzymes; / >>Metabolic pathways; / >>Nucleotide metabolism |
| Function | Catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate.,miscellaneous:Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.,PTM:Phosphorylated on Ser-13 in mitosis.,similarity:Belongs to the thymidine kinase family., |
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