U-Blot® TSPO Rabbit mAb
Product details
Background:
Present mainly in the mitochondrial compartment of peripheral tissues , the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding , and the other variants encode the same protein. [provided by RefSeq , Feb 2012]
Specifications
| Size | 50μL/100μL |
| Target | TSPO |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 19kD |
| MW(Observed) | 16kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1875R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | TSPO PBRS |
| Protein Name | Putative peripheral benzodiazepine receptor-related protein |
| Other Name | BPBS; / BZRP; / DBI; / IBP; / MBR; / PBR; / PBS; / PKBS; / PTBR; / TSPO1; / mDRC; / PK18 |
| Species | Human |
| Gene ID | 706 |
| Uniprot | B1AH88, |
| Species.1 | Mouse |
| Gene ID.1 | 12257 |
| Uniprot.1 | P50637, |
| Species.2 | Rat |
| Gene ID.2 | 24230 |
| Uniprot.2 | P16257 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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