U-Blot® ULK1 (phospho S623) Rabbit mAb

Price range: $288.00 through $368.00

SKU: WT9119-100
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Product details

Background:ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200 kDa (FIP 200). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC.

Specifications

TargetPhospho-ULK1 (Ser623)
ReactivityHuman
ApplicationWB
MW(Calculated)113 kDa
MW(Observed)130 kDa
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationPhosphorylation
Modification SiteSer623
Recommended dilution ratioWB 1:2000-1:4000
CompositionPBS, Glycerol, BSA
Purification processProtein A affinity purification
StorageStore at -20°C. Avoid repeated freeze-thaw cycles
StabilityStable for 12 months from date of receipt / reconstitution.
Concentration
ClonalRecombinant monoclonal
Clone NumberW-R78
Immunogenpolypeptide
Gene NameULK1
Protein NameSerine/threonine-protein kinase ULK1
Alternative nameKIAA0722
Organism-1Human
Gene ID8408
SwissProt-1O75385
Cellular LocalizationCytoplasm
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