U-Blot® ULK1 (phospho S623) Rabbit mAb
Ucallm_WT9119-100
Price range: $288.00 through $368.00
Product details
Background:ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200 kDa (FIP 200). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC.
Specifications
| Target | Phospho-ULK1 (Ser623) |
| Reactivity | Human |
| Application | WB |
| MW(Calculated) | 113 kDa |
| MW(Observed) | 130 kDa |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Phosphorylation |
| Modification Site | Ser623 |
| Recommended dilution ratio | WB 1:2000-1:4000 |
| Composition | PBS, Glycerol, BSA |
| Purification process | Protein A affinity purification |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonal | Recombinant monoclonal |
| Clone Number | W-R78 |
| Immunogen | polypeptide |
| Gene Name | ULK1 |
| Protein Name | Serine/threonine-protein kinase ULK1 |
| Alternative name | KIAA0722 |
| Organism-1 | Human |
| Gene ID | 8408 |
| SwissProt-1 | O75385 |
| Cellular Localization | Cytoplasm |
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