U-Blot® WTAP Rabbit mAb
Ucallm_WR5711-50
Price range: $268.00 through $328.00
Product details
Background:The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012],
Specifications
| Target | WTAP |
| Reactivity | Human |
| Applications | WB,IHC,IF,IP,ELISA |
| MW(Calculated) | 44kD |
| MW(Observed) | 55kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Modified site | |
| Recommended Dilution Ratio | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Composition | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Source | |
| Purification Process | Protein A |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | PT1505R |
| Immunogen | |
| Sequence | |
| Specificity | Endogenous |
| Gene Name | WTAP |
| Protein Name | Pre-mRNA-splicing regulator WTAP |
| Alias | WTAP;KIAA0105;Pre-mRNA-splicing regulator WTAP;Female-lethal;2;D homolog;hFL;2;D;WT1-associated protein;Wilms tumor 1-associating protein |
| Organism-1 | Human |
| Gene ID-1 | 9589 |
| SwissProt-1 | Q15007 |
| Organism-2 | Mouse |
| GeneID-2 | 60532.0 |
| SwissProt-2 | Q9ER69 |
| Organism-3 | |
| GeneID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus. . |
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