U17L2 rabbit pAb
Ucallm_WP17304-50
Price range: $268.00 through $328.00
Product details
Background:
DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.[supplied by OMIM, Mar 2008],
Specifications
| Size | 50μL/100μL |
| Target | U17L2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 58kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human U17L2 AA range: 321-371 |
| Specificity | This antibody detects endogenous levels of U17L2 at Human/Mouse |
| Gene Name | USP17L2 DUB3 |
| Protein Name | U17L2 |
| Other Name | |
| Species | Human |
| Gene ID | 377630 |
| Uniprot | Q6R6M4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q7M764 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Endoplasmic reticulum . |
| Tissue Expression | Broadly expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,Caution:The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found both on chromosome 4 and chromosome 8.,Caution:The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found in the genome both on chromosome 4 and chromosome 8.,Function:Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates.,Function:Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates. May also bind hyaluronan and RNA.,induction:Up-regulated by interleukin-4 and interleukin-6 (at protein level).,similarity:Belongs to the peptidase C19 family. USP17 subfamily.,tissue specificity:Broadly expressed.,tissue specificity:Expressed in heart, brain, liver and skeletal muscle., |
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