SKU: WP1915 Categories: ,

UB2Q1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1915-100
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Product details

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetUB2Q1
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)46kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityUB2Q1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameUBE2Q1 NICE5 UBE2Q PRO3094
Protein NameUbiquitin-conjugating enzyme E2 Q1 (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1)
Other Name
SpeciesHuman
Gene ID55585
UniprotQ7Z7E8,
Species.1Mouse
Gene ID.1
Uniprot.1Q7TSS2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Cell projection, filopodium . Cytoplasm, cytosol .
Tissue ExpressionWidely expressed.
Signaling_pathwayGenetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis
Research Areas>>Ubiquitin mediated proteolysis
FunctionCatalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,Function:Catalyzes the covalent attachment of ubiquitin to other proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed.,
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