Price range: $268.00 through $328.00
Background:
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol., function:Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the peptidase C19 family., tissue specificity:Expressed in brain at low level.,
| Size | 50μL/100μL |
| Target | USP34 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF |
| MW(Calculated) | |
| MW(Observed) | 390kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-300; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | UBP34 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | USP34 KIAA0570 KIAA0729 |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 34 |
| Other Name | Ubiquitin carboxyl-terminal hydrolase 34; / Deubiquitinating enzyme 34; / Ubiquitin thioesterase 34; / Ubiquitin-specific-processing protease 34 |
| Species | Human |
| Gene ID | 9736 |
| Uniprot | Q70CQ2, |
| Species.1 | Mouse |
| Gene ID.1 | 17847 |
| Uniprot.1 | Q6ZQ93 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | SAGA complex,cytosol, |
| Tissue Expression | Expressed in brain at low level. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,Function:Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain at low level., |
