Product details
Na+/ K+ ATPase exists in cell membrane and is an active transport enzyme that can exchange sodium and potassium ions. It was discovered by J.C. Skou in 1957. With a few exceptions, such as the red blood cell membrane of cats and dogs, it exists in all animal cell membranes. It has also been reported in bacteria, but instances are rare, and its presence in plants has not been confirmed. It is only active when Na+ and K+ are present simultaneously. During the decomposition of ATP, the enzyme molecules undergo allosteric (conformational change), which makes the bound Na+ and K+ transfer from inside the cell membrane to outside the cell membrane, or from outside the cell membrane to inside the cell membrane. It can be used as a marker for cell membranes (plasma membrane).
Application
The antibody can be applied to WB, IHC, ICC/IF, Flow Cytometry.
