SKU: WP14943 Categories: ,

Urotensin II Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14943-100
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Product details

Background:

This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetUrotensin II
ReactivityHuman, Monkey
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)14kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human Urotensin II. AA range:48-97
SpecificityUrotensin II Polyclonal Antibody detects endogenous levels of Urotensin II protein.
Gene NameUTS2
Protein NameUrotensin-2
Other NameUTS2; / Urotensin-2; / Urotensin II; / U-II; / UII
SpeciesHuman
Gene ID10911
UniprotO95399,
Species.1Mouse
Gene ID.1
Uniprot.1Q9QZQ3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue ExpressionBrain specific.
Signaling_pathway
Research Areas>>Neuroactive ligand-receptor interaction
FunctionFunction:Highly potent vasoconstrictor.,similarity:Belongs to the urotensin-2 family.,tissue specificity:Brain specific.,
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