USP22 rabbit pAb
Ucallm_WP6370-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | USP22 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 58kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human USP22 |
| Specificity | This antibody detects endogenous levels of USP22 at Human, Mouse |
| Gene Name | USP22 KIAA1063 USP3L |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 22 (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) |
| Other Name | |
| Species | Human |
| Gene ID | 23326 |
| Uniprot | Q9UPT9, |
| Species.1 | Mouse |
| Gene ID.1 | 216825 |
| Uniprot.1 | Q5DU02 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. |
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