Product details
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VATL rabbit pAb
Ucallm_WP17891-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ATP6V0C |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, WB |
| MW(Calculated) | 17kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human N-ternal VATL |
| Specificity | This antibody detects endogenous levels of VATL at Human, Mouse,Rat |
| Gene Name | ATP6V0C ATP6C ATP6L ATPL |
| Protein Name | V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (Vacuolar proton pump 16 kDa proteolipid subunit) |
| Other Name | V-type proton ATPase 16 kDa proteolipid subunit; / V-ATPase 16 kDa proteolipid subunit; / Vacuolar proton pump 16 kDa proteolipid subunit |
| Species | Human |
| Gene ID | 527 |
| Uniprot | P27449, |
| Species.1 | Mouse |
| Gene ID.1 | 11984 |
| Uniprot.1 | P63082, |
| Species.2 | Rat |
| Gene ID.2 | 170667 |
| Uniprot.2 | P63081 |
| Cellular Localization | Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Transport and catabolism >> Lysosome;Organismal Systems >> Nervous system >> Synaptic vesicle cycle;Human Diseases >> Immune disease >> Rheumatoid arthritis |
| Research Areas | |
| Function | Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). |
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