Name: VPAC2 Polyclonal Antibody
SKU: WP15000
Price: 268 USD
Availability: InStock

VPAC2 Polyclonal Antibody

Ucallm_WP15000-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP15000-100

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Product details

Background:

vasoactive intestinal peptide receptor 2(VIPR2) Homo sapiens This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011],

Specifications

Size	50μL/100μL
Target	VPAC2
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	49kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human VIPR2. AA range:83-132
Specificity	VPAC2 Polyclonal Antibody detects endogenous levels of VPAC2 protein.
Gene Name	VIPR2
Protein Name	Vasoactive intestinal polypeptide receptor 2
Other Name	VIPR2; / VIP2R; / Vasoactive intestinal polypeptide receptor 2; / VIP-R-2; / Helodermin-preferring VIP receptor; / Pituitary adenylate cyclase-activating polypeptide type III receptor; / PACAP type III receptor; / PACAP-R-3; / PACAP-R3; / VPAC2
Species	Human
Gene ID	7434
Uniprot	P41587,
Species.1	Mouse
Gene ID.1	22355
Uniprot.1	P41588,
Species.2	Rat
Gene ID.2	29555
Uniprot.2	P35000
Cellular Localization	Cell membrane; Multi-pass membrane protein.
Tissue Expression	Expressed in CD4+ T-cells, but not in CD8+ T-cells. Expressed in the T-cell lines Jurkat, Peer, MOLT-4, HSB, YT and SUP-T1, but not in the T-cell lines HARRIS and HuT 78.
Signaling_pathway	Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Research Areas	>>cAMP signaling pathway; / >>Neuroactive ligand-receptor interaction
Function	Function:This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Expressed in CD4+ T-cells, but not in CD8+ T-cells. Expressed in the T-cell lines Jurkat, PEER, MOLT-4, HSB, YT and Tsup-1, but not in the T-cell lines HARRIS and HUT 78.,

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VPAC2 Polyclonal Antibody

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VPAC2 Polyclonal Antibody

Product details

Specifications

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