Name: VRK2 Polyclonal Antibody
SKU: WP15004
Price: 268 USD
Availability: InStock

VRK2 Polyclonal Antibody

Ucallm_WP15004-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP15004-100

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Product details

Background:

vaccinia related kinase 2(VRK2) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014],

Specifications

Size	50μL/100μL
Target	VRK2
Reactivity	Human, Mouse
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	55kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human VRK2. AA range:171-220
Specificity	VRK2 Polyclonal Antibody detects endogenous levels of VRK2 protein.
Gene Name	VRK2
Protein Name	Serine/threonine-protein kinase VRK2
Other Name	VRK2; / Serine/threonine-protein kinase VRK2; / Vaccinia-related kinase 2
Species	Human
Gene ID	7444
Uniprot	Q86Y07,
Species.1	Mouse
Gene ID.1	69922
Uniprot.1	Q8BN21
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	[Isoform 1]: Cytoplasm . Endoplasmic reticulum membrane; Single-pass type IV membrane protein . Mitochondrion membrane; Single-pass type IV membrane protein . Nucleus envelope .; [Isoform 2]: Cytoplasm . Nucleus .
Tissue Expression	Isoform 1 and isoform 2 are expressed in various tumor cell lines. Expression of isoform 1 inversely correlates with ERBB2 in breast carcinomas (at protein level). Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis.
Signaling_pathway
Research Areas
Function	Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Probable serine/threonine kinase.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis.,

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VRK2 Polyclonal Antibody

Product details

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VRK2 Polyclonal Antibody

Product details

Specifications

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