Price range: $268.00 through $328.00
Background:Predicted to be involved in several processes, including filopodium assembly; positive regulation of excitatory synapse assembly; and protein homooligomerization. Predicted to be located in membrane. Predicted to be active in axon; dendrite; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
| Size | 50μL/100μL |
| Target | VSTM5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 22kD |
| MW(Observed) | 22kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-1:5000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1085R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | VSTM5,C11orf90 |
| Protein Name | V-set and transmembrane domain-containing protein 5 |
| Other Name | C11orf90 |
| Species | Human |
| Gene ID | 387804 |
| Uniprot | A8MXK1, |
| Species.1 | Mouse |
| Gene ID.1 | 69137 |
| Uniprot.1 | Q9D806 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9D806}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9D806}. Cell projection, axon {ECO:0000250|UniProtKB:Q9D806}. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | FUNCTION: Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical development in the brain. {ECO:0000250|UniProtKB:Q9D806}. |
