Product details
Background:
WBP11 rabbit pAb
Ucallm_WP7916-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | WBP11 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 71kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WBP11 |
| Specificity | This antibody detects endogenous levels of WBP11 at Human, Mouse,Rat |
| Gene Name | WBP11 NPWBP SIPP1 SNP70 |
| Protein Name | WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1) |
| Other Name | |
| Species | Human |
| Gene ID | 51729 |
| Uniprot | Q9Y2W2, |
| Species.1 | Mouse |
| Gene ID.1 | 60321 |
| Uniprot.1 | Q923D5, |
| Species.2 | Rat |
| Gene ID.2 | 100910115 |
| Uniprot.2 | Q5PQQ2 |
| Cellular Localization | Nucleus. Cytoplasm. Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin. |
| Tissue Expression | Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. |
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