Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human WDFY4
Specificity
This antibody detects endogenous levels of WDFY4 at Human
Gene Name
WDFY4 C10orf64 KIAA1607
Protein Name
WD repeat- and FYVE domain-containing protein 4
Other Name
Species
Human
Gene ID
57705
Uniprot
Q6ZS81
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Early endosome . Endoplasmic reticulum .
Tissue Expression
Signaling_pathway
Research Areas
Function
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.