Price range: $268.00 through $328.00
Background:
TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010],
| Size | 50μL/100μL |
| Target | WDR82 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 34kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WDR82 AA range: 219-269 |
| Specificity | This antibody detects endogenous levels of WDR82 at Human/Mouse |
| Gene Name | WDR82 WDR82A UNQ9342/PRO34047 |
| Protein Name | WDR82 |
| Other Name | |
| Species | Human |
| Gene ID | 80335 |
| Uniprot | Q6UXN9, |
| Species.1 | Mouse |
| Gene ID.1 | 77305 |
| Uniprot.1 | Q8BFQ4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Chromosome . Associates with chromatin (PubMed:20516061). Recruited at sites of high RNA polymerase II occupancy (By similarity). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>mRNA surveillance pathway |
| Function | Caution:The gene encoding this protein shares one overlapping exon with TMEM113.,Function:Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3.,similarity:Belongs to the WD repeat SWD2 family.,similarity:Contains 6 WD repeats.,subunit:Interacts with CUL4B. Component of the SET1 complex, at least composed of the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2/ASH2L and CXXC1/CFP1., |
