WRNIP1 rabbit pAb
Ucallm_WP8617-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | WRNIP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 73kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WRNIP1 |
| Specificity | This antibody detects endogenous levels of WRNIP1 at Human, Mouse,Rat |
| Gene Name | WRNIP1 WHIP |
| Protein Name | ATPase WRNIP1 (Werner helicase-interacting protein 1) |
| Other Name | |
| Species | Human |
| Gene ID | 56897 |
| Uniprot | Q96S55, |
| Species.1 | Mouse |
| Gene ID.1 | 78903 |
| Uniprot.1 | Q91XU0, |
| Species.2 | Rat |
| Gene ID.2 | 282835 |
| Uniprot.2 | Q8CG07 |
| Cellular Localization | Nucleus . Cytoplasm . Colocalizes with WRN in granular structures in the nucleus. . |
| Tissue Expression | Ubiquitously expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS. |
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