Price range: $268.00 through $328.00
Background:
function:Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the krueppel C2H2-type zinc-finger protein family., similarity:Contains 4 C2H2-type zinc fingers.,
| Size | 50μL/100μL |
| Target | ZN281 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 98kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | ZN281 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ZNF281 GZP1 ZBP99 |
| Protein Name | Zinc finger protein 281 (GC-box-binding zinc finger protein 1) (Transcription factor ZBP-99) (Zinc finger DNA-binding protein 99) |
| Other Name | |
| Species | Human |
| Gene ID | 23528 |
| Uniprot | Q9Y2X9, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q99LI5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Liver,Placenta,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers., |
