Price range: $268.00 through $328.00
Background:
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016],
| Size | 50μL/100μL |
| Target | ZN473 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 96kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZN473 AA range: 279-329 |
| Specificity | This antibody detects endogenous levels of ZN473 at Human/Mouse |
| Gene Name | ZNF473 KIAA1141 ZFP100 |
| Protein Name | ZN473 |
| Other Name | |
| Species | Human |
| Gene ID | 25888 |
| Uniprot | Q8WTR7, |
| Species.1 | Mouse |
| Gene ID.1 | 243963 |
| Uniprot.1 | Q8BI67 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Herpes simplex virus 1 infection |
| Function | Function:Involved in histone pre-mRNA processing, most likely by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 20 C2H2-type zinc fingers.,subunit:Interacts with the SLBP/pre-mRNA complex but not with SLBP alone., |
