Price range: $268.00 through $328.00
Background:
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011],
| Target | ZW10 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 86kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Composition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ZW10 AA range: 38-88 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ZW10 at Human/Mouse/Rat |
| Gene Name | ZW10 |
| Protein Name | ZW10 |
| Alias | |
| Organism-1 | Human |
| Gene ID-1 | 9183 |
| SwissProt-1 | O43264 |
| Organism-2 | Mouse |
| Gene ID-2 | 26951 |
| SwissProt-2 | O54692 |
| Organism-3 | Rat |
| Gene ID-3 | 363059 |
| SwissProt-3 | Q4V8C2 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle . Lipid droplet . Dynamic pattern of localization during the cell cycle. In most cells at interphase, present diffusely in the cytoplasm (PubMed:15029241). In prometaphase, associated with the kinetochore. At metaphase, detected both at the kinetochores and, most prominently, at the spindle, particularly at the spindle poles. In very early anaphase, detected on segregating kinetochores. In late anaphase and telophase, accumulates at the spindle midzone (PubMed:11590237). . |
