STAT1 α Rabbit Monoclonal antibody

Background：signal transducer and activator of transcription 1(STAT1) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Elevate your interferon signaling and transcription research with the highly specific STAT1 α Rabbit Monoclonal Antibody. Validated across diverse cell lines and optimized for Western Blot, it’s the go-to tool for investigating STAT1-mediated signal transduction, immune responses, and cancer pathways. Accelerate discoveries in molecular biology and oncology with this top-tier antibody today!