Smad2 Rabbit Monoclonal antibody

Background：The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.

Elevate your TGF-β signaling and cancer research with the highly specific Smad2 Rabbit Monoclonal Antibody. Validated across diverse cell lines and optimized for Western Blot, it’s the trusted tool for investigating Smad2-mediated cell proliferation, apoptosis, and oncogenic pathways. Accelerate discoveries in oncology and molecular biology with this top-tier antibody today!