SKU: WR4143 Categories: ,

U-Blot® TOMM20 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4143-50
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Product details

Background:function:Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore.,similarity:Belongs to the Tom20 family.,subunit:Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with TOM22.,

Specifications

Size50μL/100μL
TargetTOMM20
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)16kD
MW(Observed)16kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:500; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM0287R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameTOMM20
Protein NameMitochondrial import receptor subunit TOM20 homolog
Other NameTOMM20; / KIAA0016; / Mitochondrial import receptor subunit TOM20 homolog; / Mitochondrial 20 kDa outer membrane protein; / Outer mitochondrial membrane receptor Tom20
SpeciesHuman
Gene ID9804
UniprotQ15388,
Species.1Mouse
Gene ID.167952
Uniprot.1Q9DCC8,
Species.2Rat
Gene ID.2266601
Uniprot.2Q62760
Cellular LocalizationMembranous
Tissue ExpressionBone marrow,Brain,Cervix,Epithelium,Eye,Fibroblast,Pancreas
Signaling_pathwayCellular Processes >> Transport and catabolism >> Mitophagy - animal
Research Areas
FunctionFunction:Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore.,similarity:Belongs to the Tom20 family.,subunit:Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with TOM22.,
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