Name: U-Blot® cGAS Rabbit mAb
SKU: WR4479
Price: 268 USD
Availability: InStock

U-Blot® cGAS Rabbit mAb

RAW264.7 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

WR4479 RAW264.7 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WR4479-50

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Product details

Background:Enables several functions, including 2′,3′-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont; intracellular signal transduction; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]

Specifications

Size	50μL/100μL
Target	M21D1
Reactivity	Mouse
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	58kD
MW(Observed)	58kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM0700R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	MB21D1 cGAS C6orf150
Protein Name	M21D1
Other Name
Species	Human
Gene ID	115004
Uniprot	Q8N884
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm, Nucleus
Tissue Expression	Expressed in the monocytic cell line THP1.
Signaling_pathway	Organismal Systems >> Immune system >> Cytosolic DNA-sensing pathway
Research Areas	>>Cytosolic DNA-sensing pathway; / >>Shigellosis; / >>Human cytomegalovirus infection; / >>Herpes simplex virus 1 infection; / >>Human immunodeficiency virus 1 infection; / >>Coronavirus disease - COVID-19
Function