Name: alpha Lactalbumin Monoclonal Antibody [9E9]
SKU: WM1021
Price: 268 USD
Availability: InStock

alpha Lactalbumin Monoclonal Antibody [9E9]

Ucallm_WM1021-50

Price range: $268.00 through $328.00

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SKU: WM1021-50

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Product details

Background:
This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1, 4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	LALBA
Reactivity	Human
Applications	WB, IHC, IF
MW(Calculated)
MW(Observed)	16kD
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:1000; IF 1:200; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	9E9
Immunogen	Synthetic Peptide of alpha Lactalbumin
Specificity	The antibody detects endogenous alpha Lactalbumin proteins.
Gene Name	LALBA
Protein Name	Alpha-lactalbumin
Other Name	Alpha-lactalbumin; / Lactose synthase B protein; / Lysozyme-like protein 7
Species	Human
Gene ID	3906
Uniprot	P00709,
Species.1	Mouse
Gene ID.1	16770
Uniprot.1	P29752,
Species.2	Rat
Gene ID.2	24528
Uniprot.2	P00714
Cellular Localization	Secreted.
Tissue Expression	Mammary gland specific. Secreted in milk.
Signaling_pathway
Research Areas	>>Galactose metabolism; / >>Metabolic pathways
Function	Function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.,similarity:Belongs to the glycosyl hydrolase 22 family.,subunit:Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).,tissue specificity:Mammary gland specific. Secreted in milk.,

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alpha Lactalbumin Monoclonal Antibody [9E9]

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alpha Lactalbumin Monoclonal Antibody [9E9]

Product details

Specifications

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