SKU: WM1753 Categories: ,

S100P [ABT375] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1753-50
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Product details

Background:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetS100P
ReactivityHuman
ApplicationsIHC, IF, ELISA
MW(Calculated)10kD
MW(Observed)
Host SpeciesMouse
IsotypeIgG1,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-400; IF 1:50-200; ELISA 1:500-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationThe antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMM375
ImmunogenSynthesized peptide derived from human S100P AA range: 1-95
SpecificityThe antibody can specifically recognize human S100P protein.
Gene NameS100P S100E
Protein NameMIG9; Migration inducing gene 9; Protein S100-E; Protein S100-P; Protein S100P; S100 calcium binding protein P; S100 calcium-binding protein P; S100 P; S100E; S100P; S100P_HUMAN
Other NameMIG9; / Migration inducing gene 9; / Protein S100-E; / Protein S100-P; / Protein S100P; / S100 calcium binding protein P; / S100 calcium-binding protein P; / S100 P; / S100E; / S100P; / S100P_HUMAN
SpeciesHuman
Gene ID6286
UniprotP25815
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNuclear, Cytoplasmic
Tissue ExpressionPlacenta/ Appendix
Signaling_pathway
Research Areas
Functionmiscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,
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