SKU: WM0370 Categories: ,

PEA3 Monoclonal Antibody

Price range: $268.00 through $328.00

SKU: WM0370-50
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Product details

Background:
function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5′[AC]GGA[AT]GT-3′., similarity:Belongs to the ETS family., similarity:Contains 1 ETS DNA-binding domain.,

Specifications

Size50μL/100μL
TargetPEA3
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)54kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationAffinity purification
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number20F11
ImmunogenPurified recombinant fragment of human PEA3 (aa50-109) expressed in E. Coli.
SpecificityPEA3 Monoclonal Antibody detects endogenous levels of PEA3 protein.
Gene NameETV4
Protein NameETS translocation variant 4
Other NameETV4; / E1AF; / PEA3; / ETS translocation variant 4; / Adenovirus E1A enhancer-binding protein; / E1A-F; / Polyomavirus enhancer activator 3 homolog; / Protein PEA3
SpeciesHuman
Gene ID2118
UniprotP43268,
Species.1Mouse
Gene ID.1
Uniprot.1P28322
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionExpressed in keratinocytes.
Signaling_pathwayHuman Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Research Areas>>Transcriptional misregulation in cancer
FunctionFunction:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,
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