SKU: WM0642 Categories: ,

LRRFIP1 mouse mAb

Price range: $268.00 through $328.00

SKU: WM0642-50
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Product details

Background:
developmental stage:Widely expressed in fetal tissues., function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5′-AGCCCCCGGCG-3′) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the LRRFIP family., subunit:Interacts with FLII., tissue specificity:Ubiquitously expressed.,

Specifications

Size50μL/100μL
TargetLRRFIP1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)
MW(Observed)160kD
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:1000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number15C7
ImmunogenPurified recombinant human LRRFIP1 protein fragments expressed in E.coli.
SpecificityThis antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins.
Gene NameLRRFIP1
Protein NameLeucine-rich repeat flightless-interacting protein 1
Other NameFLAP1; / FLIIAP 1; / GC binding factor 2; / GCF2; / HUFI1; / Leucine rich repeat; / in FLII; / interacting protein 1; / Leucine rich repeat flightless interacting protein 1; / LRR FLII interacting protein 1; / LRRFIP 1; / Lrrfip1; / MGC10947; / MGC119738; / MGC119739; / NEDD8 conjugating enzyme; / TAR RNA interacting protein; / TAR RNA-interacting protein; / Transcription factor 9 like; / TRIP.
SpeciesHuman
Gene ID9208
UniprotQ32MZ4,
Species.1Mouse
Gene ID.1
Uniprot.1Q3UZ39
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus. Cytoplasm.
Tissue ExpressionUbiquitously expressed.
Signaling_pathway
Research Areas
Functiondevelopmental stage:Widely expressed in fetal tissues.,Function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA.,sequence Caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the LRRFIP family.,subunit:Interacts with FLII.,tissue specificity:Ubiquitously expressed.,
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