D-Lactyllysine Specific Antibody Conjugated Agarose Beads

$999.00

SKU: WT9162B-300
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Product details

D-Lactyllysine Specific Antibody Conjugated Agarose Beads is an immunoaffinity enrichment tool for D-lactyl lysine peptides in mass spectrometry-based proteomics. The highly specific antibody selectively captures target modified peptides without cross-reactivity, is applicable to all species, efficiently enriches low-abundance peptides and reduces background interference, delivering stable and reliable results for D-lactyl lysine modification research.

Specifications

TargetD-Lactyllysine
ReactivitySpecies Independent
ApplicationIAC
MW(Calculated)
MW(Observed)
Host SpeciesRabbit
Isotype
ConjugateAgarose Beads
ModificationLysine lactylation
Modified siteLys(K)
Recommended dilution ratio
Composition50/250 μL settled agarose beads supplied as 50% slurry, containing 66% glycerol
Purification process
Purity
StorageStore at-20°C and avoid freezing.
StabilityStable for 12 months from date of receipt
ClonalMonoclonal
Clone Number
Immunogen
Sequence
Specificity
Gene name
Protein Name
Alternative nameKD-la
Organism-1
GeneID-1
SwissProt-1
Organism-2
GeneID-2
SwissProt-2
Organism-3
GeneID-3
SwissProt-3
Organism-4
GeneID-4
SwissProt-4
BackgroundD-Lactyllysine (K₍D_x001e_la₎) is the D_x001e_stereoisomer of lysine lactylation, a novel type of lysine acylation post_x001e_translational modification. By conjugating a D_x001e_lactyl group to lysine residues, K₍D_x001e_la₎ is mainly generated via non_x001e_enzymatic pathways from glycolysis byproducts and exists on both histone and non_x001e_histone proteins. It participates in chromatin remodeling, gene transcription, and cellular metabolic stress responses, and is closely associated with tumorigenesis, inflammation, metabolic reprogramming, and other pathological processes, serving as a key target in metabolic_x001e_epigenetic crosstalk research.
Cellular Localization
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