Price range: $268.00 through $328.00
Background：
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix , where the mature form is found. [provided by RefSeq , Jul 2008] ,
| Size | 50μL/100μL |
| Target | Citrate Synthetase |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 52kD |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1864R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | CS |
| Protein Name | CISY |
| Other Name | Citrate Synthetase |
| Species | Human |
| Gene ID | 1431 |
| Uniprot | O75390, |
| Species.1 | Mouse |
| Gene ID.1 | 12974 |
| Uniprot.1 | Q9CZU6, |
| Species.2 | Rat |
| Gene ID.2 | 170587 |
| Uniprot.2 | Q8VHF5 |
| Cellular Localization | Mitochondrion matrix. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Citrate cycle (TCA cycle); / >>Glyoxylate and dicarboxylate metabolism; / >>Metabolic pathways; / >>Carbon metabolism; / >>2-Oxocarboxylic acid metabolism; / >>Biosynthesis of amino acids |
| Function | Catalytic activity:Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.,miscellaneous:Citrate synthase is found in nearly all cells capable of oxidative metabolism.,online information:Citrate synthase entry,pathway:Carbohydrate metabolism; tricarboxylic acid cycle.,sequence Caution:Intron retention.,similarity:Belongs to the citrate synthase family.,subunit:Homodimer., |
