U-Blot® Histone H2AZ Rabbit mAb

Price range: $888.00 through $999.00

SKU: WT8488-50
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Product details

Background:
Histone H2AZ is a highly conserved H2A variant independent of DNA replication. It is specifically deposited in gene promoters, enhancers and heterochromatin regions, and regulates chromatin stability and gene transcription. H2AZ participates in key biological processes including cell differentiation, DNA damage repair, stem cell pluripotency maintenance and genome stability regulation. Abnormal expression of H2AZ is closely associated with tumor occurrence and developmental disorders.

Specifications

TargetHistone H2AZ
ReactivityAll Vertebrates
ApplicationWB, ICC. ELISA, Luminex
MW(Calculated)14kD
MW(Observed)
Host SpeciesRabbit
IsotypeRabbit IgG
ConjugateUnconjugated
ModificationUnmodified
Modified site
Recommended dilution ratioWB 0.1 ug/mL – 0.5 ug/mL; ICC 1 μg/mL - 2 μg/mL; ELISA 0.1 ug/mL - 1 ug/mL; Luminex 0.1 ug/mL – 1 ug/mL.
Composition50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
Purification processProtein A affinity purified from an animal origin-free culture supernatant
Purity
Storage-20.0°C
Concentration1 mg/mL
ClonalityRecombinant Monoclonal
Clone NumberWR-235
ImmunogenA peptide corresponding to the C-terminus of human Histone H2AZ
Sequence
SpecificityThis antibody reacts to Histone H2AZ protein, independent of post-translational modifications. No cross reactivity with other histone proteins.
Gene name
Protein Name
Alternative nameH2AZ, H2A.Z, H2AFZ, H2A/z, H2AZ1
Organism-1Human
Gene ID-13015
SwissProt-1P0C0S5
Organism-2
Gene ID-2
SwissProt-2
Organism-3
GeneID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular Localization
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