Price range: $268.00 through $328.00
Background:The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq , Jul 2008] ,
| Size | 50μL/100μL |
| Target | LAMP1 |
| Reactivity | Mouse |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 44kD |
| MW(Observed) | 115kD |
| Host Species | Rabbit |
| Isotype | IgG, Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year (Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM2203R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | LAMP1 |
| Protein Name | Lysosome-associated membrane glycoprotein 1 |
| Other Name | LAMP1; / Lysosome-associated membrane glycoprotein 1; / LAMP-1; / Lysosome-associated membrane protein 1; / CD107 antigen-like family member A; / CD107a |
| Species | Human |
| Gene ID | 3916 |
| Uniprot | P11279, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P11438, |
| Species.2 | Rat |
| Gene ID.2 | 25328 |
| Uniprot.2 | P14562 |
| Cellular Localization | Membrane |
| Tissue Expression | Brain ,Liver ,Pancreas ,Placenta ,Plasma ,Testis , |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Transport and catabolism >> Lysosome;Cellular Processes >> Transport and catabolism >> Autophagy - animal |
| Research Areas | >>Autophagy - animal; / >>Lysosome; / >>Phagosome; / >>Tuberculosis |
| Function | Function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. ,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. ,similarity:Belongs to the LAMP family. ,subcellular location:This protein shuttles between lysosomes , endosomes , and the plasma membrane. , |
