Specifications
| Size | 50μL/100μL |
| Target | MYH7 |
| Reactivity | Human, Mouse, Rat, Pig |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 223kD |
| MW(Observed) | 223kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1048R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | MYH7 MYHCB |
| Protein Name | Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta) |
| Other Name | |
| Species | Human |
| Gene ID | 4625 |
| Uniprot | P12883, |
| Species.1 | Mouse |
| Gene ID.1 | 140781 |
| Uniprot.1 | Q91Z83, |
| Species.2 | Rat |
| Gene ID.2 | 29557 |
| Uniprot.2 | P02564 |
| Cellular Localization | Cytoplasm, myofibril . Cytoplasm, myofibril, sarcomere . Thick filaments of the myofibrils. . |
| Tissue Expression | Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level). |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway;Organismal Systems >> Circulatory system >> Cardiac muscle contraction;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway |
| Research Areas | >>cGMP-PKG signaling pathway; / >>Cardiac muscle contraction; / >>Adrenergic signaling in cardiomyocytes; / >>Thyroid hormone signaling pathway; / >>Hypertrophic cardiomyopathy; / >>Dilated cardiomyopathy; / >>Viral myocarditis |
| Function |
