Specifications
| Size | 50μL/100μL |
| Target | TOMM40 |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 38kD |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1178R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | TOMM40 C19orf1 PEREC1 TOM40 |
| Protein Name | Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5) |
| Other Name | |
| Species | Human |
| Gene ID | 10452 |
| Uniprot | O96008, |
| Species.1 | Mouse |
| Gene ID.1 | 53333 |
| Uniprot.1 | Q9QYA2, |
| Species.2 | Rat |
| Gene ID.2 | 308416 |
| Uniprot.2 | Q75Q40 |
| Cellular Localization | Mitochondrion outer membrane; Multi-pass membrane protein . Associates with the mitochondria-associated ER membrane via interaction with BCAP31. . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Mitophagy - animal;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases |
| Research Areas | |
| Function | Channel-forming protein essential for import of protein precursors into mitochondria . Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria . |
