SKU: WP0798 Categories: ,

RLA1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0798-100
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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively splic

Specifications

Size50μL/100μL
TargetRLA1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)12kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 30-110
SpecificityRLA1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameRPLP1 RRP1
Protein Name60S acidic ribosomal protein P1
Other Name
SpeciesHuman
Gene ID6176
UniprotP05386,
Species.1Mouse
Gene ID.1
Uniprot.1P47955,
Species.2Rat
Gene ID.2
Uniprot.2P19944
Cellular Localizationcytoplasm,cytosol,ribosome,focal adhesion,cytosolic large ribosomal subunit,preribosome, large subunit precursor,extracellular exosome,
Tissue ExpressionEpithelium,Eye,Hepatocyte,Pituitary,Placenta,Platelet,T-cel
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
FunctionFunction:Plays an important role in the elongation step of protein synthesis.,similarity:Belongs to the ribosomal protein L12P family.,subunit:P1 and P2 exist as dimers at the large ribosomal subunit.,
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