SKU: WP2716 Categories: ,

VSIG1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2716-100
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Product details

Background:

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],

Specifications

Size50μL/100μL
TargetVSIG1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)42kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 1-80
SpecificityVSIG1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameVSIG1 GPA34
Protein NameV-set and immunoglobulin domain-containing protein 1 (Cell surface A33 antigen) (Glycoprotein A34)
Other Name
SpeciesHuman
Gene ID340547
UniprotQ86XK7,
Species.1Mouse
Gene ID.1
Uniprot.1Q9D2J4,
Species.2Rat
Gene ID.2
Uniprot.2Q4KLY3
Cellular LocalizationMembrane; Single-pass type I membrane protein .
Tissue ExpressionDetected only in stomach mucosa and testis, and to a much lesser level in pancreas (at protein level). Detected in gastric cancers (31%), esophageal carcinomas (50%) and ovarian cancers (23%).
Signaling_pathway
Research Areas
FunctionPTM:Highly N-glycosylated. Appears not to contain significant amounts of O-linked carbohydrates or sialic acid in its sugar moieties.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Detected only in stomach mucosa and testis, and to a much lesser lever in pancreas (at protein level). Detected in gastric cancers (31%), esophageal carcinomas (50%) and ovarian cancers (23%).,
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