SKU: WP2895 Categories: ,

5HT3B Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2895-100
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Product details

Background:

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011],

Specifications

Target5HT3B
ReactivityHuman, Rat, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)48kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000;ELISA 1:5000-20000
CompositionLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 140-220
Sequence
Specificity5HT3B Polyclonal Antibody detects endogenous levels of protein.
Gene NameHTR3B
Protein Name5-hydroxytryptamine receptor 3B (5-HT3-B) (5-HT3B) (Serotonin receptor 3B)
Alias
Organism-1Human
Gene ID-19177
SwissProt-1O95264
Organism-2Mouse
Gene ID-2
SwissProt-2Q9JHJ5
Organism-3Rat
Gene ID-3
SwissProt-3Q9JJ16
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCell membrane ; Multi-pass membrane protein . Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
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