Name: SSR5 Polyclonal Antibody
SKU: WP2931
Price: 268 USD
Availability: InStock

SSR5 Polyclonal Antibody

Ucallm_WP2931-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP2931-100

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Product details

Background:

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010],

Specifications

Size	50μL/100μL
Target	SSR5
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	40kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 270-350
Specificity	SSR5 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	SSTR5
Protein Name	Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R)
Other Name
Species	Human
Gene ID	6755
Uniprot	P35346,
Species.1	Mouse
Gene ID.1
Uniprot.1	O08858,
Species.2	Rat
Gene ID.2
Uniprot.2	P30938
Cellular Localization	Cell membrane; Multi-pass membrane protein.
Tissue Expression	Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.
Signaling_pathway	Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action;Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Research Areas	>>cAMP signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Growth hormone synthesis, secretion and action
Function	Function:Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.,