Product details
Background:
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MER34 rabbit pAb
Ucallm_WP3517-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MER34 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MER34 AA range: 391-441 |
| Specificity | This antibody detects endogenous levels of MER34 at Human |
| Gene Name | ERVMER34-1 LP9056 |
| Protein Name | MER34 |
| Other Name | HERV-MER_4q12 provirus ancestral Env polyprotein; / Endogenous retrovirus group MER34 member 1 |
| Species | Human |
| Gene ID | 100288413 |
| Uniprot | Q9H9K5 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Endogenous retroviral envelope protein HEMO]: Cell membrane; Single-pass type I membrane protein . This uncleaved form present at the cell surface represents the major form (PubMed:28739914). .; [Endogenous retroviral envelope protein HEMO, secreted form]: Secreted . This secreted form, which is released in the extracellular medium following cleavage, constitutes a minor form (PubMed:28739914). . |
| Tissue Expression | Expressed at high level in the placenta and stem cells (at protein level) (PubMed:28739914). Also expressed in the kidney but at a lower level (PubMed:28739914). Endogenous retroviral envelope protein HEMO, secreted form: Present in the blood of pregnant women (at protein level) (PubMed:28739914). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.,similarity:Belongs to the gamma type-C retroviral envelope protein family., |
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