Product details
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AL2CL rabbit pAb
Ucallm_WP3629-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AL2CL |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AL2CL AA range: 606-656 |
| Specificity | This antibody detects endogenous levels of AL2CL at Human/Mouse |
| Gene Name | ALS2CL |
| Protein Name | AL2CL |
| Other Name | ALS2 C-terminal-like protein |
| Species | Human |
| Gene ID | 259173 |
| Uniprot | Q60I27, |
| Species.1 | Mouse |
| Gene ID.1 | 235633 |
| Uniprot.1 | Q60I26 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells. |
| Tissue Expression | Expressed in heart and kidney. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.,similarity:Contains 1 VPS9 domain.,similarity:Contains 8 MORN repeats.,subcellular location:Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells.,subunit:Homodimer. Forms a heteromeric complex with ALS2 (By similarity). Interacts with ALS2 and RAB5A.,tissue specificity:Expressed in heart and kidney., |
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