IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SPR2D AA range: 16-66
Specificity
This antibody detects endogenous levels of SPR2D at Human/Mouse
Gene Name
SPRR2D
Protein Name
SPR2D
Other Name
Species
Human
Gene ID
6703
Uniprot
P22532,
Species.1
Mouse
Gene ID.1
20758
Uniprot.1
O70555
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm.
Tissue Expression
Signaling_pathway
Research Areas
Function
Function:Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.,induction:During squamous differentiation of epidermal keratinocytes.,similarity:Belongs to the cornifin (SPRR) family.,