Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human INCA1 AA range: 10-60
Specificity
This antibody detects endogenous levels of INCA1 at Human/Mouse
Gene Name
INCA1 HSD45
Protein Name
INCA1
Other Name
Species
Human
Gene ID
388324
Uniprot
Q0VD86,
Species.1
Mouse
Gene ID.1
103844
Uniprot.1
Q6PKN7
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Cytoplasm .
Tissue Expression
Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors (PubMed:15159402). Down-regulated in bone marrow cells in acute myeloid and lymphoid leukemia patients as compared with normal bone marrow cells (PubMed:21540187).
Signaling_pathway
Research Areas
Function
PTM:Phosphorylated when part of a complex with CCNA1 and CDK2. Strongly phosphorylated by CDK2 on its C-terminal region spanning amino acid 149-221. Less intensively phosphorylated by CDK2 on its first 75 amino acid residues.,similarity:Belongs to the INCA family.,subunit:Interacts with CCNA1. Identified in a complex with CCNA1 and CDK2.,tissue specificity:Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors.,