INCA1 rabbit pAb
Ucallm_WP4318-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | INCA1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 26kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human INCA1 AA range: 10-60 |
| Specificity | This antibody detects endogenous levels of INCA1 at Human/Mouse |
| Gene Name | INCA1 HSD45 |
| Protein Name | INCA1 |
| Other Name | |
| Species | Human |
| Gene ID | 388324 |
| Uniprot | Q0VD86, |
| Species.1 | Mouse |
| Gene ID.1 | 103844 |
| Uniprot.1 | Q6PKN7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . |
| Tissue Expression | Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors (PubMed:15159402). Down-regulated in bone marrow cells in acute myeloid and lymphoid leukemia patients as compared with normal bone marrow cells (PubMed:21540187). |
| Signaling_pathway | |
| Research Areas | |
| Function | PTM:Phosphorylated when part of a complex with CCNA1 and CDK2. Strongly phosphorylated by CDK2 on its C-terminal region spanning amino acid 149-221. Less intensively phosphorylated by CDK2 on its first 75 amino acid residues.,similarity:Belongs to the INCA family.,subunit:Interacts with CCNA1. Identified in a complex with CCNA1 and CDK2.,tissue specificity:Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors., |
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