SKU: WP4868 Categories: ,

KAZRN rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4868-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetKAZRN
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)85kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:1000-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human KAZRN AA range: 125-175
SpecificityThis antibody detects endogenous levels of human KAZRN
Gene NameKAZN KAZ KIAA1026 HRIHFB2003
Protein NameKazrin
Other Name
SpeciesHuman
Gene ID23254
UniprotQ674X7,
Species.1Mouse
Gene ID.171529
Uniprot.1Q69ZS8,
Species.2Rat
Gene ID.271529
Uniprot.2Q5FWS6
Cellular LocalizationCytoplasm, cytoskeleton .; [Isoform 2]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 3]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 4]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
Tissue ExpressionIsoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).
Signaling_pathway
Research Areas
Function
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