Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human KAZRN AA range: 125-175
Specificity
This antibody detects endogenous levels of human KAZRN
Gene Name
KAZN KAZ KIAA1026 HRIHFB2003
Protein Name
Kazrin
Other Name
Species
Human
Gene ID
23254
Uniprot
Q674X7,
Species.1
Mouse
Gene ID.1
71529
Uniprot.1
Q69ZS8,
Species.2
Rat
Gene ID.2
71529
Uniprot.2
Q5FWS6
Cellular Localization
Cytoplasm, cytoskeleton .; [Isoform 2]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 3]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 4]: Cytoplasm. Cell junction, desmosome. Nucleus. Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
Tissue Expression
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).