The protein encoded by this gene is an autophagy factor and a target of the TOR kinase signaling pathway. The encoded protein is essential for autophagosome formation and mitophagy. [provided by RefSeq, Oct 2016],
Specifications
Target
ATG13
Reactivity
Human, Mouse, Rat
Applications
IHC, IF
MW(Calculated)
MW(Observed)
57kD
Host Species
Rabbit
Isotype
IgG
Conjugate
Modification
Unmodified
Recommended Dilution Ratio
IHC 1:50-300;IF 1:50-200
Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification Process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Recombinant Protein of ATG13
Sequence
Specificity
The antibody detects endogenous ATG13 protein
Gene Name
ATG13 KIAA0652
Protein Name
Autophagy-related protein 13
Alias
Autophagy-related protein 13
Organism-1
Human
Gene ID-1
9776
SwissProt-1
O75143
Organism-2
Mouse
Gene ID-2
SwissProt-2
Q91YI1
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular Localization
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .